| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPAC2H10.01.1 | SPAC30D11.11.1 | SPAC2H10.01.1 | SPAC30D11.11.1 | transcription factor, zf-fungal binuclear cluster type (predicted) | Haemolysin-III family protein (predicted) | 0.769 |
| SPAC2H10.01.1 | nep2 | SPAC2H10.01.1 | SPBC32H8.02c.1 | transcription factor, zf-fungal binuclear cluster type (predicted) | NEDD8 protease Nep2; Protease that catalyzes two essential functions in the NEDD8 pathway- processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as the pcu1, pcu2 and pcu4 cullins and other proteins (By similarity). Has a role in meiosis | 0.925 |
| SPAC2H10.01.1 | plb1 | SPAC2H10.01.1 | SPAC1A6.04c.1 | transcription factor, zf-fungal binuclear cluster type (predicted) | phospholipase B homolog Plb1; Catalyzes the release of fatty acids from lysophospholipids. Required for survival under high osmolarity, for normal osmotic stress-induced gene expression, and for nutrient-mediated repression of sexual differentiation | 0.520 |
| SPAC30D11.11.1 | SPAC2H10.01.1 | SPAC30D11.11.1 | SPAC2H10.01.1 | Haemolysin-III family protein (predicted) | transcription factor, zf-fungal binuclear cluster type (predicted) | 0.769 |
| SPAC30D11.11.1 | nep2 | SPAC30D11.11.1 | SPBC32H8.02c.1 | Haemolysin-III family protein (predicted) | NEDD8 protease Nep2; Protease that catalyzes two essential functions in the NEDD8 pathway- processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as the pcu1, pcu2 and pcu4 cullins and other proteins (By similarity). Has a role in meiosis | 0.662 |
| SPAC30D11.11.1 | plb1 | SPAC30D11.11.1 | SPAC1A6.04c.1 | Haemolysin-III family protein (predicted) | phospholipase B homolog Plb1; Catalyzes the release of fatty acids from lysophospholipids. Required for survival under high osmolarity, for normal osmotic stress-induced gene expression, and for nutrient-mediated repression of sexual differentiation | 0.468 |
| crp79 | nep2 | SPAC1610.03c.1 | SPBC32H8.02c.1 | poly(A) binding protein Crp79; Binds the poly(A) tail of mRNA. Involved in the export of mRNA from the nucleus to the cytoplasm | NEDD8 protease Nep2; Protease that catalyzes two essential functions in the NEDD8 pathway- processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as the pcu1, pcu2 and pcu4 cullins and other proteins (By similarity). Has a role in meiosis | 0.668 |
| csn5 | cul1 | SPAC1687.13c.1 | SPAC17G6.12.1 | COP9/signalosome complex subunit Csn5; Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity) | cullin 1; Core component of multiple cullin-RING-based SCF (SKP1- CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(pop1-pop2) is required for the maintenance of ploidy and directs ubiquitination of cig2 | 0.996 |
| csn5 | ned8 | SPAC1687.13c.1 | SPBC12D12.08c.1 | COP9/signalosome complex subunit Csn5; Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity) | ubiquitin-like protein modifier Ned8 | 0.954 |
| csn5 | nep1 | SPAC1687.13c.1 | SPBC17D11.01.1 | COP9/signalosome complex subunit Csn5; Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity) | NEDD8 protease Nep1; Protease that catalyzes two essential functions in the NEDD8 pathway- processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as the pcu1, pcu2 and pcu4 cullins and other proteins | 0.940 |
| csn5 | nep2 | SPAC1687.13c.1 | SPBC32H8.02c.1 | COP9/signalosome complex subunit Csn5; Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity) | NEDD8 protease Nep2; Protease that catalyzes two essential functions in the NEDD8 pathway- processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as the pcu1, pcu2 and pcu4 cullins and other proteins (By similarity). Has a role in meiosis | 0.759 |
| csn5 | uch1 | SPAC1687.13c.1 | SPAC27F1.03c.1 | COP9/signalosome complex subunit Csn5; Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity) | ubiquitin C-terminal hydrolase Uch1; Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin (By similarity) | 0.985 |
| csn5 | uch2 | SPAC1687.13c.1 | SPBC409.06.1 | COP9/signalosome complex subunit Csn5; Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity) | ubiquitin C-terminal hydrolase Uch2; Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin | 0.814 |
| cul1 | csn5 | SPAC17G6.12.1 | SPAC1687.13c.1 | cullin 1; Core component of multiple cullin-RING-based SCF (SKP1- CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(pop1-pop2) is required for the maintenance of ploidy and directs ubiquitination of cig2 | COP9/signalosome complex subunit Csn5; Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity) | 0.996 |
| cul1 | ned8 | SPAC17G6.12.1 | SPBC12D12.08c.1 | cullin 1; Core component of multiple cullin-RING-based SCF (SKP1- CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(pop1-pop2) is required for the maintenance of ploidy and directs ubiquitination of cig2 | ubiquitin-like protein modifier Ned8 | 0.999 |
| cul1 | nep1 | SPAC17G6.12.1 | SPBC17D11.01.1 | cullin 1; Core component of multiple cullin-RING-based SCF (SKP1- CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(pop1-pop2) is required for the maintenance of ploidy and directs ubiquitination of cig2 | NEDD8 protease Nep1; Protease that catalyzes two essential functions in the NEDD8 pathway- processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as the pcu1, pcu2 and pcu4 cullins and other proteins | 0.867 |
| cul1 | nep2 | SPAC17G6.12.1 | SPBC32H8.02c.1 | cullin 1; Core component of multiple cullin-RING-based SCF (SKP1- CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(pop1-pop2) is required for the maintenance of ploidy and directs ubiquitination of cig2 | NEDD8 protease Nep2; Protease that catalyzes two essential functions in the NEDD8 pathway- processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as the pcu1, pcu2 and pcu4 cullins and other proteins (By similarity). Has a role in meiosis | 0.867 |
| ned8 | csn5 | SPBC12D12.08c.1 | SPAC1687.13c.1 | ubiquitin-like protein modifier Ned8 | COP9/signalosome complex subunit Csn5; Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity) | 0.954 |
| ned8 | cul1 | SPBC12D12.08c.1 | SPAC17G6.12.1 | ubiquitin-like protein modifier Ned8 | cullin 1; Core component of multiple cullin-RING-based SCF (SKP1- CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(pop1-pop2) is required for the maintenance of ploidy and directs ubiquitination of cig2 | 0.999 |
| ned8 | nep1 | SPBC12D12.08c.1 | SPBC17D11.01.1 | ubiquitin-like protein modifier Ned8 | NEDD8 protease Nep1; Protease that catalyzes two essential functions in the NEDD8 pathway- processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as the pcu1, pcu2 and pcu4 cullins and other proteins | 0.984 |
